Esther Blodgett is just another starry-eyed farm kid trying to break into the movies. Waitressing at a Hollywood party, she catches the eye of her idol Norman Maine, is sent for a screen test, and before long attains stardom as newly minted Vicki Lester. She and Norman marry, though his career soon dwindles to nothing due to his chronic alcoholism.
Art editor Madeleine Damian carries on numerous loveless affairs. After a failed relationship with advertiser Felix Courtland, the increasingly depressed Madeleine attempts suicide. When Jack Garet, her secretary and former lover, tries to blackmail her, Madeleine resigns and seeks a reclusive life. Neighbor David Cousins befriends Madeleine, but soon Courtland and Garet discover her whereabouts and disrupt her new life.