Esther Blodgett is just another starry-eyed farm kid trying to break into the movies. Waitressing at a Hollywood party, she catches the eye of her idol Norman Maine, is sent for a screen test, and before long attains stardom as newly minted Vicki Lester. She and Norman marry, though his career soon dwindles to nothing due to his chronic alcoholism.
A bedridden and gravely ill man believes his wife and doctor are conspiring to kill him, and outlines his suspicions in a letter.
As a parting shot, fired reporter Ann Mitchell prints a fake letter from unemployed "John Doe," who threatens suicide in protest of social ills. The paper is forced to rehire Ann and hires John Willoughby to impersonate "Doe." Ann and her bosses cynically milk the story for all it's worth, until the made-up "John Doe" philosophy starts a whole political movement.
Walter Burns is an irresistibly conniving newspaper publisher desperate to woo back his paper’s star reporter, who also happens to be his estranged wife. She’s threatening to quit and settle down with a new beau, but, as Walter knows, she has a weakness: she can’t resist a juicy scoop.