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With the help of her friends, Emily moves to a remote home to take better care of her brother, Zack who is diagnosed with cerebral palsy. But what they don't know is that the house is keeping a terrifying secret that will haunt them one by one.
Dr. Bill Cortner and his fiancée, Jan Compton, are driving to his lab when they get into a horrible car accident. Compton is decapitated. But Cortner is not fazed by this seemingly insurmountable hurdle. His expertise is in transplants, and he is excited to perform the first head transplant. Keeping Compton's head alive in his lab, Cortner plans the groundbreaking yet unorthodox surgery. First, however, he needs a body.
Professor Morlant, a British Egyptologist, seeks immortality through the power of a jewel buried in the tomb of an Oriental idol. Upon his death, Morlant returns to earth to seek vengeance upon those who removed the jewel from his grave.
Dr. Paul Carruthers is frustrated because he thinks his employers, Mary Heath and Henry Morton, have cheated him out of the company's profits. He decides to get revenge by altering bats to grow twice their normal size and training them to attack when they smell a perfume of his own making. He mixes the perfume into a lotion, which he offers as a gift to Mary and Henry. When they turn up dead, a newspaper reporter decides to investigate.