A rich Easterner who has always wanted to live in "the Wild West" plans to move to a Western town. Unknown to him, the town's "wild" days are long gone and it is an orderly and civilized place now. The townsmen, not wanting to lose a rich potential resident, contrive to make over the town to suit the young man's fantasy.
France, on the eve of the French Revolution. Henriette and Louise have been raised together as sisters. When the plague that takes their parents' lives causes Louise's blindness, they decide to travel to Paris in search of a cure, but they separate when a lustful aristocrat crosses their path.
Two families, abolitionist Northerners the Stonemans and Southern landowners the Camerons, intertwine. When Confederate colonel Ben Cameron is captured in battle, nurse Elsie Stoneman petitions for his pardon. In Reconstruction-era South Carolina, Cameron founds the Ku Klux Klan, battling Elsie's congressman father and his African-American protégé, Silas Lynch.
The story of a poor young woman, separated by prejudice from her husband and baby, is interwoven with tales of intolerance from throughout history.